Anjarium Biosciences is a cell and gene therapy tools and technology company headquartered in Switzerland.
Our mission is to enable researchers and manufacturers to accelerate the discovery and delivery cycle of new and evolving genetic medicines. Our technology enables our partners to meet biology’s greatest challenges with increasingly flexible and customizable DNA constructs in pursuit of better human health.
Technology
At Anjarium, we help our customers optimize their R&D and manufacturing workflows by delivering synthetic DNA products with unprecedented speed and customization. We deliver faster, cleaner, infinitely flexible, high-fidelity, hairpin-ended, linear, double-stranded DNA products to accelerate the development and delivery of advanced therapies across diverse modalities.
The benefits of the Anjarium DNA platform include:
Unmatched speed of production and delivery – in a fraction of the time for traditional plasmid
The scale you need – from microgram to multigram quantities
The highest product consistency, stability, and quality
Customizable terminal DNA structures and complex transgene sequences for a variety of applications
Unmatched speed of production and delivery – in a fraction of the time for traditional plasmid
The scale you need – from microgram to multigram quantities
The highest product consistency, stability, and quality
Customizable terminal DNA structures and complex transgene sequences for a variety of applications
We have designed a one-pot reaction that generates linear, double-stranded DNA with customizable hairpin-ended structures. The integrity of the DNA sequence of interest is protected by these structures, which are inspired by nature and play a functional role in certain applications.
Our enzymatic DNA synthesis approach
Our one-pot reaction generates cleaner, high-fidelity, hairpin-ended, linear, double-stranded DNA products with unprecedented speed and customization.
Services
Infinitely flexible, highly scalable synthetic DNA customized to support your needs
We offer a range of products to support research, development, and commercialization of genetic medicines.
Our cell-free platform creates pure, customizable, and flexible synthetic linear DNA constructs for a wide variety of therapeutic modalities – all scaled to your needs.
Why are our products different?
Purity Unlike with plasmid-based systems, no bacterial sequences are used in production, reducing the risk of unwanted elements and DNA backbone components in end product
Scale Our process scales from microgram to multigram batches while using a small bioreactor and minimal reagents
Speed Production time from circular DNA template to vial delivery of weeks rather than months for plasmid-based techniques
Stability Hairpin-ended structures protect the integrity of the double-stranded DNA sequences
Flexibility Complex and customized transgene sequences beyond what can be delivered by bacteria-derived DNA
Solutions
What can we do for you?
Discovery
Preclinical
Clinical
Commercial
RUO
Catalog products
Bespoke products
Candidate screening
In vivo testing
Toxicity studies
GMP
In vivo testing
Toxicity studies
HQ GMP
GMP
GMP
Discovery
RUO
Catalog products
Bespoke products
Candidate screening
GMP
Preclinical
RUO
In vivo testing
Toxicity studies
GMP
In vivo testing
Toxicity studies
Clinical
RUO
GMP
HQ GMP
GMP
Commercial
RUO
GMP
GMP
Facilities
Schlieren: Innovation and R&D center
Analytical development and QC fully equipped
Executing according to ISO9001 principles
Basel: GMP manufacturing facility
GMP certification in progress
RUO, HQ GMP, and GMP
Swissmedic awarded advanced therapy medical products (ATMP) license for cell therapy production in 2022
DNA offerings
AAV
ITR stability with significant improvement in yields
Catalog: Rep/Cap and Helper, Luciferase and GFP reporters in multiple serotypes
Bespoke: GOI, Helper and Rep/Cap with full serotype capabilities
mRNA
Less DNA required for equivalent yields
Catalog: Luciferase and GFP reporters
Bespoke sequences with stable Poly-ApolyA tails up to 140+
Lentivirus
Production of all constructs including GOI with long terminal repeat (LTR) sequences
HDR and other applications
Design and manufacturing services to create custom constructs
AAV
ITR stability with significant improvement in yields
Catalog: Rep/Cap and Helper, Luciferase and GFP reporters in multiple serotypes
Bespoke: GOI, Helper and Rep/Cap with full serotype capabilities
mRNA
Less DNA required for equivalent yields
Catalog: Luciferase and GFP reporters
Bespoke sequences with stable Poly-ApolyA tails up to 140+
Lentivirus
Production of all constructs including GOI with long terminal repeat (LTR) sequences
HDR and other applications
Design and manufacturing services to create custom constructs
Contact us about how Anjarium DNA services and products can help your company.
Our team of innovative scientists and manufacturing experts are relentless problem-solvers committed to creating new possibilities for genetic medicines through synthetic, enzymatically produced DNA.
Our Leadership team and Board of Directors bring deep development, manufacturing, and commercialization experience from leading global life science companies.
Anjarium is proud to partner with leading life science investors.
Investors include Abingworth, Gimv, Omega Funds, Pfizer Ventures, and Surveyor Capital (a Citadel company).
Careers
Join us to accelerate the development and delivery of novel, life-changing medicines to patients.
Anjarium is assembling a world-class global team to accelerate access to revolutionary cell and gene therapies with next generation tools and technology.
